Protocol Type: Endotoxin
Protocol Name: NCL Method STE-1.4: Detection and Quantification of Gram-Negative Bacterial Endotoxin Contamination in Nanoparticle Formulations Using the Kinetic Chromogenic LAL Assay
Protocol Abbreviation: STE-1.4
Protocol Version: 3
DOI: http://dx.doi.org/10.17917/B6HB-C950
Protocol File: 20240410_14-46-46-749_NCL_Method_STE-1.4.pdf
File Title: STE-1.4
Description: This document describes a protocol for a quantitative detection of Gram-negative bacterial endotoxin in nanoparticle preparations using a kinetic chromogenic Limulus Amebocyte Lysate (LAL) assay. The protocol is based on the USP standard 85 “Bacterial endotoxin test.”
Resource Type: Protocol
Data Access: https://general.datacommons.cancer.gov/#/data