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caNanoLab DOI


Protocol Type: Endotoxin

Protocol Name: NCL Method STE-1.2: Detection and Quantification of Gram-Negative Bacterial Endotoxin Contamination in Nanoparticle Formulations Using the Kinetic Turbidity LAL Assay

Protocol Abbreviation: STE-1.2

Protocol Version: 1.3


DOI: http://dx.doi.org/10.17917/2EEV-MY50

Protocol File: 20250124_13-02-51-506_NCL_Method_STE-1.2.pdf

File Title: STE-1.2

Description: This document describes a protocol for a quantitative detection of Gram-negative bacterial endotoxin in nanoparticle preparations using a kinetic turbidity Limulus Amebocyte Lysate (LAL) assay. The protocol is based on the USP standard 85 “Bacterial endotoxin test.”


Resource Type: Protocol

Data Access: https://general.datacommons.cancer.gov/#/data