Protocol Type: in vitro assay
Protocol Name: NCL Method ITA-2.2: Analysis of Platelet Aggregation by Light Transmission Aggregometry
Protocol Abbreviation: ITA-2.2
Protocol Version: 3
DOI: http://dx.doi.org/10.17917/7GEJ-8G77
Protocol File: 20240410_19-02-17-339_NCL_Method_ITA-2.2.pdf
File Title: ITA-2.2
Description: This document describes a procedure for analysis of platelet aggregation. Platelet-rich plasma (PRP) is obtained from fresh human whole blood and incubated with either a control or test sample. Platelet Poor Plasma (PPP) is used as a background control. The instrument records change in the light transmission through PRP which occurs when platelets aggregate resulting in a decrease in the sample turbidity. In addition, the instrument allows measuring ATP release indicative of platelet activation.
Resource Type: Protocol
Data Access: https://general.datacommons.cancer.gov/#/data