Protocol Type: in vitro assay
Protocol Name: NCL Method ITA-3: Mouse Granulocyte-Macrophage Colony-Forming Unit Assay
Protocol Abbreviation: ITA-3
Protocol Version: 4
DOI: http://dx.doi.org/10.17917/YTHD-KF51
Protocol File: 20240410_19-05-34-575_NCL_Method_ITA-3.pdf
File Title: ITA-3
Description: Myelosuppression is a common dose limiting toxicity of cytotoxic oncology drugs. Nanoparticles may distribute to bone marrow and/or release drug that is delivered to bone marrow. Therefore, understanding potential toxicity of nanoparticles or drugs which nanoparticles carry is an important step in preclinical safety evaluation. The protocol described here details the in vitro CFU-GM study.
Resource Type: Protocol
Data Access: https://general.datacommons.cancer.gov/#/data