The Molecular Biology sub-domain represents the core concepts related to this domain, including gene, protein, molecular biomarker, and numerous other related concepts.  This sub-domain is meant to contain just enough concepts to support the PGx domains in CDISC's SDTM and potential interfaces with the future domain analysis model being developed by the Clinical Genomics work group of HL7.  That model is the natural home of these concepts and that work group has the subject matter expertise to manage the model which BRIDG will eventually just reference.<br/><br/><font color="#ff0000"><b>Collaboration with other HL7 Work Groups</b>: With the broader scope of BRIDG 4.0 covering translational research and the harmonization of Life Sciences Model and CDISC Pharmogenomic & Pharmocogenetics domains, it is likely that there is some overlap of concepts between BRIDG Molecular Biology subdomain concepts and the models being developed in the HL7 Clinical Genomics (CG) work group.  BRIDG recognizes the Clinical Genomics work group models as peer or sibling models and is committed to working with the CG team to align on common semantics.  The BRIDG team has started the conversation with the CG work group to this effect and plan to continue the dialogue on how to operationalize the collaboration and leverage the subject matter expertise of this HL7 CG group members.  </font><br/>