: Public Class
Created: 9/11/2013 2:21:32 PM
Modified: 8/26/2017 2:24:22 AM
Project:
Advanced:
DEFINITION:<br/>A measurable and quantifiable biological parameter which serves as index for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc. [Source: adapted from MESH]<br/><br/>EXAMPLE(S):<br/>Specific enzyme concentration<br/>Specific hormone concentration<br/>Specific gene phenotype distribution in a population<br/>Presence of biological substances<br/><br/>OTHER NAME(S):<br/><br/>NOTE(S):<br/>
Attribute
Public ST
  name
Details:
Map:LSDAMv2.2.3Plus=Biomarker.name
Map:PGx v1.0=PB.PBMRKR
Notes: DEFINITION:<br/>The textual identifier for the biomarker as provided by the assigning source.<br/><br/>EXAMPLE(S):<br/>p.G48V<br/>p.L10I<br/>p.K20R<br/>p.M36I<br/>p.A71V<br/>p.V82T<br/><br/>OTHER NAME(S):<br/><br/>NOTE(S):<br/>
Public CD
  typeCode
Details:
Map:LSDAMv2.2.3Plus=Biomarker.typeCode
Notes: DEFINITION:<br/>A coded value specifying the basis of the biomarker.  <br/><br/>EXAMPLE(S):<br/>Genetic, Protein, Image-based<br/><br/>OTHER NAME(S):<br/><br/>NOTE(S):<br/>
Element Source Role Target Role
NucleicAcidSequenceFeature
Class   		Name: basingBiomarker
  		Name: basedNucleicAcidSequenceFeature
 
Details:
DESCRIPTION:<br/>Each Biomarker might be based on one or more NucleicAcidSequenceFeature.  Each NucleicAcidSequenceFeature might be the basis of one or more Biomarker.<br/><br/>DEFINITION:<br/><br/>EXAMPLE(S):<br/><br/>OTHER NAME(S):<br/><br/>NOTE(S):<br/>
PerformedObservationResult
Class   		Name: basingBiomarker
  		Name: basedPerformedObservationResult
 
Details:
DESCRIPTION:<br/>Each Biomarker might be based on one or more PerformedObservationResult.  Each PerformedObservationResult might be the basis of one or more Biomarker.<br/><br/>DEFINITION:<br/><br/>EXAMPLE(S):<br/>An image annotation might be the basis for a biomarker.<br/><br/>OTHER NAME(S):<br/><br/>NOTE(S):<br/>
Protein
Class   		Name: basingBiomarker
  		Name: basedProtein
 
Details:
DESCRIPTION:<br/>Each Biomarker might be based on one or more Protein. Each Protein might be the basis of one or more Biomarker.<br/><br/>DEFINITION:<br/><br/>EXAMPLE(S):<br/><br/>OTHER NAME(S):<br/><br/>NOTE(S):<br/>
Element Source Role Target Role
PerformedObservationResult
Class   		Name: establishingPerformedObservationResult
  		Name: establishedBiomarker
 
Details:
DESCRIPTION:<br/>Each PerformedObservationResult might establish one or more Biomarker.  Each Biomarker might be established by one or more PerformedObservationResult.<br/><br/>DEFINITION:<br/>Identifies the finding that results in the identification of a biomarker.<br/><br/>EXAMPLE(S):<br/><br/>OTHER NAME(S):<br/><br/>NOTE(S):<br/>
Tag Value
Map:LSDAMv2.2.3Plus Biomarker
Details:
 
Object Type Connection Direction Notes
MolecularBiomarker Class Generalization From DESCRIPTION: Each MolecularBiomarker always specializes one Biomarker. Each Biomarker might be specialized by one MolecularBiomarker. DEFINITION: EXAMPLE(S): OTHER NAME(S): NOTE(S):